In this project Metal Organic Framework of UiO-66-NH2 was synthetised by reaction of Zr(NO3)4 and 2-aminotherphetalic acid with controlling factors such as tempereture, solvent and pH.Then by Post Synthetic Modification method through using ClSO3H, the MOF functionalized under Nitrogen gas and SO3H group directly linked on the NH2 groups of this Metal Organic Frameworks (MOF) linker. Results were confirmed by Infrared Spectroscopy. Then the functionalized MOF used as a catalyst for the production of benzimidazoles derivatives and reductive amination of carbonyl compounds and reacted as a well hetrogeneous catalyst. The advantages of this catalyst are, easy separation by centrifuging from reaction mixture, recyclability and reuse it for several consecutive times without decreas in its catalytic activity.
The results showed that in the presence of the catalyst products are obtained with high efficiency in a short time

 Stipa capensis, the Mediterranean needle-grass, is an annual grass of the genus stipa, in the Poaceae family. It is normal found in the Persian Gulf desert ad semi-desert biome. This plant is indigenous to the fars, Khozestan, and west of iran. In traditional medicine, stipa capensis have been used for illness related to the Nerve system problems and gastric discords. The gole of this study is to identify and characterize the phytochemical compound present in this valuable medicinal plant. This is the frist report of the presence of phytochemical in stipa capensis. Stipa capensis is commonly known as Bahman in Iran. The leaves of the plant Stipa capensis was collected from Masjede-Soleiman, Khouzestant, Iran in March , 2015. Basic phytochemical screening from the aerial parts of stipa capensis revealed the presence of terpenoids and steroids. The powdered sample was extracted and was further fractionated successively with n-hexane and methanol.The nonpolar fraction was subjected to column.The separated constituents were subjected to LC-MS and GC-MS study. The spectrum of the unknown compounds was compared with the spectrum of the component stored in the NIST (National Institute Standard and Technology) library. The results pertaining to LC-MS analysis led to the identification of number of terpenes from fraction of the hexane extract of Stipa capensis.This is the frist report of the screening and isolation of phytochemical in stipa capensis.This study reports the isolation and identification of terpenoid extracted from stipa capensis on fraction 1and 4 isolated that led to isolation of terpenoid compounds (carotenoids, steroids, cardiac glycosides and prenol lipids.)

 The reductive amination of carbonyl compound is one of the most useful reactions for the synthesis of amines and their derivatives as essential siological and pharmaceutical active compounds.
There is several solid catalyst have been developed for reductive amonation.
In this project, we used B(OSO3H)3/SiO2 as green and recoverable hetrogeneus catalyst. the reductive amination of carbonyl compound for preparation of secondery and tertiary amine was achived via one-pot reaction in the presence of thise catalyst.
The results showed that product was obtained in good yield and short time.
The advantages of this progect are: mild condition and short reaction time, reaction in solvent and under free-solvent condition.

 

In this project, by using optimized structure of compounds in the multi component synthesis of iminopyranes, we tried to study the propose mechanism reaction.
We used B3LYP6/311++G(d,p), as the basis set to analyze the hirshfeld, mulliken and NBO parameters. We also found some electronic, structure and optice properties. In the second project we use the theoretical study of the aromaticity of carbazol derivatives to find the effect of nitrogen in the different rings and how affect the aromaticity of central pyrole ring.
 

The inconvenience of functional groups as a problem in the synthesis of complex organic compounds from the investigations of Emil Fischer on carbohydrates until now, has been remained.
In multi-functional compounds synthesized, a reactive functional group is temporarily blocked by incorporating a suitable protecting group, this issue was one of the most important of Fischer research results. It is especially very practicable and important in the synthesis of complex organic molecules such as, peptides, nucleotides and carbohydrates.
In this project, according to the importance of functional group protection in the synthesis of complex compounds, the protection of amines, alcohols and thiols in the presence of corrected silica with boron sulfonic acid catalyst was investigated. For this purpose Di-tert-butyl dicarbonate and formic acid reagents were used to protect the functional groups.
Results obtained from both reactions, indicating the effectiveness of an acid catalyst to protect amines and alcohols, particularly amines, because amines nucleophilic strength is more than alcohols and thiols. Moreover the results obtained shows the high selectivity of this method.
Simplicity, mild reaction conditions, solventless reaction and high yield are properties of this method.